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Recent advances of pathomics in colorectal cancer diagnosis and prognosis
Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals h...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396402/ https://www.ncbi.nlm.nih.gov/pubmed/37538112 http://dx.doi.org/10.3389/fonc.2023.1094869 |
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author | Wu, Yihan Li, Yi Xiong, Xiaomin Liu, Xiaohua Lin, Bo Xu, Bo |
author_facet | Wu, Yihan Li, Yi Xiong, Xiaomin Liu, Xiaohua Lin, Bo Xu, Bo |
author_sort | Wu, Yihan |
collection | PubMed |
description | Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals have been facilitated by the fast development of artificial intelligence (AI) -based algorithms using radiological and pathological data, in combination with genomic information. Among them, features extracted from pathological images, termed pathomics, are able to reflect sub-visual characteristics linking to better stratification and prediction of therapeutic responses. In this paper, we review recent advances in pathological image-based algorithms in CRC, focusing on diagnosis of benign and malignant lesions, micro-satellite instability, as well as prediction of neoadjuvant chemoradiotherapy and the prognosis of CRC patients. |
format | Online Article Text |
id | pubmed-10396402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103964022023-08-03 Recent advances of pathomics in colorectal cancer diagnosis and prognosis Wu, Yihan Li, Yi Xiong, Xiaomin Liu, Xiaohua Lin, Bo Xu, Bo Front Oncol Oncology Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals have been facilitated by the fast development of artificial intelligence (AI) -based algorithms using radiological and pathological data, in combination with genomic information. Among them, features extracted from pathological images, termed pathomics, are able to reflect sub-visual characteristics linking to better stratification and prediction of therapeutic responses. In this paper, we review recent advances in pathological image-based algorithms in CRC, focusing on diagnosis of benign and malignant lesions, micro-satellite instability, as well as prediction of neoadjuvant chemoradiotherapy and the prognosis of CRC patients. Frontiers Media S.A. 2023-07-19 /pmc/articles/PMC10396402/ /pubmed/37538112 http://dx.doi.org/10.3389/fonc.2023.1094869 Text en Copyright © 2023 Wu, Li, Xiong, Liu, Lin and Xu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Wu, Yihan Li, Yi Xiong, Xiaomin Liu, Xiaohua Lin, Bo Xu, Bo Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title | Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title_full | Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title_fullStr | Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title_full_unstemmed | Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title_short | Recent advances of pathomics in colorectal cancer diagnosis and prognosis |
title_sort | recent advances of pathomics in colorectal cancer diagnosis and prognosis |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396402/ https://www.ncbi.nlm.nih.gov/pubmed/37538112 http://dx.doi.org/10.3389/fonc.2023.1094869 |
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