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Recent advances of pathomics in colorectal cancer diagnosis and prognosis

Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals h...

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Autores principales: Wu, Yihan, Li, Yi, Xiong, Xiaomin, Liu, Xiaohua, Lin, Bo, Xu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396402/
https://www.ncbi.nlm.nih.gov/pubmed/37538112
http://dx.doi.org/10.3389/fonc.2023.1094869
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author Wu, Yihan
Li, Yi
Xiong, Xiaomin
Liu, Xiaohua
Lin, Bo
Xu, Bo
author_facet Wu, Yihan
Li, Yi
Xiong, Xiaomin
Liu, Xiaohua
Lin, Bo
Xu, Bo
author_sort Wu, Yihan
collection PubMed
description Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals have been facilitated by the fast development of artificial intelligence (AI) -based algorithms using radiological and pathological data, in combination with genomic information. Among them, features extracted from pathological images, termed pathomics, are able to reflect sub-visual characteristics linking to better stratification and prediction of therapeutic responses. In this paper, we review recent advances in pathological image-based algorithms in CRC, focusing on diagnosis of benign and malignant lesions, micro-satellite instability, as well as prediction of neoadjuvant chemoradiotherapy and the prognosis of CRC patients.
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spelling pubmed-103964022023-08-03 Recent advances of pathomics in colorectal cancer diagnosis and prognosis Wu, Yihan Li, Yi Xiong, Xiaomin Liu, Xiaohua Lin, Bo Xu, Bo Front Oncol Oncology Colorectal cancer (CRC) is one of the most common malignancies, with the third highest incidence and the second highest mortality in the world. To improve the therapeutic outcome, the risk stratification and prognosis predictions would help guide clinical treatment decisions. Achieving these goals have been facilitated by the fast development of artificial intelligence (AI) -based algorithms using radiological and pathological data, in combination with genomic information. Among them, features extracted from pathological images, termed pathomics, are able to reflect sub-visual characteristics linking to better stratification and prediction of therapeutic responses. In this paper, we review recent advances in pathological image-based algorithms in CRC, focusing on diagnosis of benign and malignant lesions, micro-satellite instability, as well as prediction of neoadjuvant chemoradiotherapy and the prognosis of CRC patients. Frontiers Media S.A. 2023-07-19 /pmc/articles/PMC10396402/ /pubmed/37538112 http://dx.doi.org/10.3389/fonc.2023.1094869 Text en Copyright © 2023 Wu, Li, Xiong, Liu, Lin and Xu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wu, Yihan
Li, Yi
Xiong, Xiaomin
Liu, Xiaohua
Lin, Bo
Xu, Bo
Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title_full Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title_fullStr Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title_full_unstemmed Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title_short Recent advances of pathomics in colorectal cancer diagnosis and prognosis
title_sort recent advances of pathomics in colorectal cancer diagnosis and prognosis
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396402/
https://www.ncbi.nlm.nih.gov/pubmed/37538112
http://dx.doi.org/10.3389/fonc.2023.1094869
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