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An empirical investigation into the impact of winner’s curse on estimates from Mendelian randomization
INTRODUCTION: Genetic associations for variants identified through genome-wide association studies (GWASs) tend to be overestimated in the original discovery data set as, if the association was underestimated, the variant may not have been detected. This bias, known as winner’s curse, can affect Men...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396423/ https://www.ncbi.nlm.nih.gov/pubmed/36573802 http://dx.doi.org/10.1093/ije/dyac233 |