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Lactate secreted by esophageal cancer cells induces M2 macrophage polarization via the AKT/ERK pathway

BACKGROUND: Elevated lactate results in an acidic tumor microenvironment (TME), which stimulates the progression of esophageal cancer (EC). Tumor‐associated macrophages (TAMs) are an essential component of the TME. However, the regulatory mechanisms of lactate secreted by EC on TAMs and the effects...

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Detalles Bibliográficos
Autores principales:	Zhang, Chunsheng, Cheng, Wei, Yang, Tongjin, Fang, Hanlin, Zhang, Renquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396787/ https://www.ncbi.nlm.nih.gov/pubmed/37345237 http://dx.doi.org/10.1111/1759-7714.14998

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