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Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions

Biomolecular condensates, protein-rich and dynamic membrane-less organelles, play critical roles in a range of subcellular processes, including membrane trafficking and transcriptional regulation. However, aberrant phase transitions of intrinsically disordered proteins in biomolecular condensates ca...

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Detalles Bibliográficos
Autores principales: Maltseva, Daria, Chatterjee, Sayantan, Yu, Chun-Chieh, Brzezinski, Mateusz, Nagata, Yuki, Gonella, Grazia, Murthy, Anastasia C., Stachowiak, Jeanne C., Fawzi, Nicolas L., Parekh, Sapun H., Bonn, Mischa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10396963/
https://www.ncbi.nlm.nih.gov/pubmed/37231298
http://dx.doi.org/10.1038/s41557-023-01221-1