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Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents

Voltage-gated sodium channels (Na(v)) are key players in excitable tissues with the capability to generate and propagate action potentials. Mutations in the genes encoding Na(v)s can lead to severe inherited diseases, and some of these so-called channelopathies show temperature-sensitive phenotypes,...

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Detalles Bibliográficos
Autores principales: Kriegeskorte, Sophia, Bott, Raya, Hampl, Martin, Korngreen, Alon, Hausmann, Ralf, Lampert, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397059/
https://www.ncbi.nlm.nih.gov/pubmed/37531097
http://dx.doi.org/10.1085/jgp.202213312

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