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Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents
Voltage-gated sodium channels (Na(v)) are key players in excitable tissues with the capability to generate and propagate action potentials. Mutations in the genes encoding Na(v)s can lead to severe inherited diseases, and some of these so-called channelopathies show temperature-sensitive phenotypes,...
Autores principales: | Kriegeskorte, Sophia, Bott, Raya, Hampl, Martin, Korngreen, Alon, Hausmann, Ralf, Lampert, Angelika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397059/ https://www.ncbi.nlm.nih.gov/pubmed/37531097 http://dx.doi.org/10.1085/jgp.202213312 |
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