Crystal structures of main protease (M(pro)) mutants of SARS-CoV-2 variants bound to PF-07304814

There is an urgent need to develop effective antiviral drugs to prevent the viral infection caused by constantly circulating SARS-CoV-2 as well as its variants. The main protease (M(pro)) of SARS-CoV-2 is a salient enzyme that plays a vital role in viral replication and serves as a fascinating thera...

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Detalles Bibliográficos
Autores principales: Jiang, Haihai, Zou, Xiaofang, Zeng, Pei, Zeng, Xiangyi, Zhou, Xuelan, Wang, Jie, Zhang, Jin, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397169/
https://www.ncbi.nlm.nih.gov/pubmed/37532968
http://dx.doi.org/10.1186/s43556-023-00134-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397169/
https://www.ncbi.nlm.nih.gov/pubmed/37532968
http://dx.doi.org/10.1186/s43556-023-00134-2

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