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Neonatal lupus erythematosus manifested as a complete heart block: A case report

KEY CLINICAL MESSAGE: Fetal bradycardia and congenital complete heart block could be the presentation of neonatal lupus. A high index of suspicion of this condition helps to identify an asymptomatic mother. ABSTRACT: Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease of newborn...

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Detalles Bibliográficos
Autores principales: Gyawali, Siddinath, Rauniyar, Suraj Prasad Gupta, Gyawali, Bindu, Bhusal, Tapasya, Basnet, Srijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397475/
https://www.ncbi.nlm.nih.gov/pubmed/37546163
http://dx.doi.org/10.1002/ccr3.7758
Descripción
Sumario:KEY CLINICAL MESSAGE: Fetal bradycardia and congenital complete heart block could be the presentation of neonatal lupus. A high index of suspicion of this condition helps to identify an asymptomatic mother. ABSTRACT: Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease of newborns due to placental transfer of Ro/SSA or La/SSB autoantibodies. Though cardiac, cutaneous, hematological, and hepatobiliary abnormalities are detected, cardiac defects cause significant morbidity and mortality. We report a case of complete congenital heart block due to NLE.