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SGIP1 in axons prevents internalization of desensitized CB1R and modifies its function

In the central nervous system (CNS), cannabinoid receptor 1 (CB1R) is preferentially expressed in axons where it has a unique property, namely resistance to agonist-driven endocytosis. This review aims to summarize what we know about molecular mechanisms of CB1R cell surface stability in axonal comp...

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Detalles Bibliográficos
Autores principales: Durydivka, Oleh, Mackie, Ken, Blahos, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397514/
https://www.ncbi.nlm.nih.gov/pubmed/37547151
http://dx.doi.org/10.3389/fnins.2023.1213094