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Blockage of S100A8/A9 ameliorates septic nephropathy in mice

Septic acute kidney injury (AKI) is the commonest cause of complication of sepsis in intensive care units, but its pathophysiology remains unclear. Calprotectin (S100A8/A9), which is a damage-associated molecular patterns (DAMPs) molecule, exerts a critical role in modulating leukocyte recruitment a...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Wan, Tian-Tian, Li, Hui-Hua, Guo, Shu-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398385/
https://www.ncbi.nlm.nih.gov/pubmed/37547329
http://dx.doi.org/10.3389/fphar.2023.1172356