Identification of microbial metabolites that accelerate the ubiquitin-dependent degradation of c-Myc

Myc belongs to a family of proto-oncogenes that encode transcription factors. The overexpression of c-Myc causes many types of cancers. Recently, we established a system for screening c-Myc inhibitors and identified antimycin A by screening the RIKEN NPDepo chemical library. The specific mechanism o...

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Detalles Bibliográficos
Autores principales: LIU, ZIYU, OKANO, AKIKO, SANADA, EMIKO, FUTAMURA, YUSHI, NOGAWA, TOSHIHIKO, ISHIKAWA, KOSUKE, SEMBA, KENTARO, LI, JIANG, LI, XIAOMENG, OSADA, HIROYUKI, WATANABE, NOBUMOTO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tech Science Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398403/
https://www.ncbi.nlm.nih.gov/pubmed/37547761
http://dx.doi.org/10.32604/or.2023.030248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398403/
https://www.ncbi.nlm.nih.gov/pubmed/37547761
http://dx.doi.org/10.32604/or.2023.030248

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