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Kawasaki Disease: A Never-ending Story?

The most severe complication of Kawasaki disease, an inflammatory disorder of young children, is the formation of coronary artery aneurysms. It is known that patients with coronary artery aneurysms, particularly those with medium and large lesions, have a higher risk of future major cardiovascular e...

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Autores principales: Lianza, Alessandro Cavalcanti, Diniz, Maria de Fátima Rodrigues, Sawamura, Karen Saori Shiraishi, Menezes, Carolina da Rocha Brito, de Sousa Lobo Silva, Isabela, Leal, Gabriela Nunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398426/
https://www.ncbi.nlm.nih.gov/pubmed/37546182
http://dx.doi.org/10.15420/ecr.2023.15
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author Lianza, Alessandro Cavalcanti
Diniz, Maria de Fátima Rodrigues
Sawamura, Karen Saori Shiraishi
Menezes, Carolina da Rocha Brito
de Sousa Lobo Silva, Isabela
Leal, Gabriela Nunes
author_facet Lianza, Alessandro Cavalcanti
Diniz, Maria de Fátima Rodrigues
Sawamura, Karen Saori Shiraishi
Menezes, Carolina da Rocha Brito
de Sousa Lobo Silva, Isabela
Leal, Gabriela Nunes
author_sort Lianza, Alessandro Cavalcanti
collection PubMed
description The most severe complication of Kawasaki disease, an inflammatory disorder of young children, is the formation of coronary artery aneurysms. It is known that patients with coronary artery aneurysms, particularly those with medium and large lesions, have a higher risk of future major cardiovascular events. In contrast, there is a lack of data on the cardiovascular status in long-term follow-up for Kawasaki disease patients without coronary involvement or with self-limited coronary artery aneurysms, resulting in most patients being discharged after 5 years. Even though some paediatricians may believe these patients should not be followed at all, studies indicating a dysfunctional endothelium show the need for further investigation. Consequently, a review of the most significant aspects of Kawasaki disease, and the necessity of correctly identifying, treating and monitoring these patients, particularly those with a higher risk of complications, was conducted.
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spelling pubmed-103984262023-08-04 Kawasaki Disease: A Never-ending Story? Lianza, Alessandro Cavalcanti Diniz, Maria de Fátima Rodrigues Sawamura, Karen Saori Shiraishi Menezes, Carolina da Rocha Brito de Sousa Lobo Silva, Isabela Leal, Gabriela Nunes Eur Cardiol Management and Comorbidities The most severe complication of Kawasaki disease, an inflammatory disorder of young children, is the formation of coronary artery aneurysms. It is known that patients with coronary artery aneurysms, particularly those with medium and large lesions, have a higher risk of future major cardiovascular events. In contrast, there is a lack of data on the cardiovascular status in long-term follow-up for Kawasaki disease patients without coronary involvement or with self-limited coronary artery aneurysms, resulting in most patients being discharged after 5 years. Even though some paediatricians may believe these patients should not be followed at all, studies indicating a dysfunctional endothelium show the need for further investigation. Consequently, a review of the most significant aspects of Kawasaki disease, and the necessity of correctly identifying, treating and monitoring these patients, particularly those with a higher risk of complications, was conducted. Radcliffe Cardiology 2023-07-27 /pmc/articles/PMC10398426/ /pubmed/37546182 http://dx.doi.org/10.15420/ecr.2023.15 Text en Copyright © The Author(s), 2023. Published by Radcliffe Group Ltd. https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Management and Comorbidities
Lianza, Alessandro Cavalcanti
Diniz, Maria de Fátima Rodrigues
Sawamura, Karen Saori Shiraishi
Menezes, Carolina da Rocha Brito
de Sousa Lobo Silva, Isabela
Leal, Gabriela Nunes
Kawasaki Disease: A Never-ending Story?
title Kawasaki Disease: A Never-ending Story?
title_full Kawasaki Disease: A Never-ending Story?
title_fullStr Kawasaki Disease: A Never-ending Story?
title_full_unstemmed Kawasaki Disease: A Never-ending Story?
title_short Kawasaki Disease: A Never-ending Story?
title_sort kawasaki disease: a never-ending story?
topic Management and Comorbidities
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398426/
https://www.ncbi.nlm.nih.gov/pubmed/37546182
http://dx.doi.org/10.15420/ecr.2023.15
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