Cargando…
Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria
BACKGROUND: Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available. OBJECTIVES: To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients. METHODS: A cross-sectional study of 86 adult patients hos...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Makerere Medical School
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398429/ https://www.ncbi.nlm.nih.gov/pubmed/37545917 http://dx.doi.org/10.4314/ahs.v23i1.9 |
_version_ | 1785084054418227200 |
---|---|
author | Adekanmbi, Olukemi Ilesanmi, Olayinka Idowu, Olusola Esan, Arinola Raji, Yemi R Fowotade, Adeola Ogunlade, Olubunmi Akere, Adegboyega Ololade, Oluwaseun Ojifinni, Kehinde Akinola, Olurotimi Orunmuyi, Akintunde Eze, Uwom Akinmoladun, Victor Adeoye, Abiodun Adebiyi, Akindele Olapade-Olaopa, E Oluwabunmi Otegbayo, Jesse A Osungbade, Kayode |
author_facet | Adekanmbi, Olukemi Ilesanmi, Olayinka Idowu, Olusola Esan, Arinola Raji, Yemi R Fowotade, Adeola Ogunlade, Olubunmi Akere, Adegboyega Ololade, Oluwaseun Ojifinni, Kehinde Akinola, Olurotimi Orunmuyi, Akintunde Eze, Uwom Akinmoladun, Victor Adeoye, Abiodun Adebiyi, Akindele Olapade-Olaopa, E Oluwabunmi Otegbayo, Jesse A Osungbade, Kayode |
author_sort | Adekanmbi, Olukemi |
collection | PubMed |
description | BACKGROUND: Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available. OBJECTIVES: To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients. METHODS: A cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors. RESULTS: Mean age was 60.9±16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71±22% and 38±11/minute in non-survivors and 90±7% and 31±7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001). CONCLUSION: Most of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization. |
format | Online Article Text |
id | pubmed-10398429 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Makerere Medical School |
record_format | MEDLINE/PubMed |
spelling | pubmed-103984292023-08-04 Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria Adekanmbi, Olukemi Ilesanmi, Olayinka Idowu, Olusola Esan, Arinola Raji, Yemi R Fowotade, Adeola Ogunlade, Olubunmi Akere, Adegboyega Ololade, Oluwaseun Ojifinni, Kehinde Akinola, Olurotimi Orunmuyi, Akintunde Eze, Uwom Akinmoladun, Victor Adeoye, Abiodun Adebiyi, Akindele Olapade-Olaopa, E Oluwabunmi Otegbayo, Jesse A Osungbade, Kayode Afr Health Sci Articles BACKGROUND: Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available. OBJECTIVES: To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients. METHODS: A cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors. RESULTS: Mean age was 60.9±16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71±22% and 38±11/minute in non-survivors and 90±7% and 31±7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001). CONCLUSION: Most of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization. Makerere Medical School 2023-03 /pmc/articles/PMC10398429/ /pubmed/37545917 http://dx.doi.org/10.4314/ahs.v23i1.9 Text en © 2023 Adekanmbi O et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Adekanmbi, Olukemi Ilesanmi, Olayinka Idowu, Olusola Esan, Arinola Raji, Yemi R Fowotade, Adeola Ogunlade, Olubunmi Akere, Adegboyega Ololade, Oluwaseun Ojifinni, Kehinde Akinola, Olurotimi Orunmuyi, Akintunde Eze, Uwom Akinmoladun, Victor Adeoye, Abiodun Adebiyi, Akindele Olapade-Olaopa, E Oluwabunmi Otegbayo, Jesse A Osungbade, Kayode Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title | Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title_full | Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title_fullStr | Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title_full_unstemmed | Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title_short | Characteristics and outcomes of patients hospitalized with COVID-19 at a tertiary hospital in Nigeria |
title_sort | characteristics and outcomes of patients hospitalized with covid-19 at a tertiary hospital in nigeria |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398429/ https://www.ncbi.nlm.nih.gov/pubmed/37545917 http://dx.doi.org/10.4314/ahs.v23i1.9 |
work_keys_str_mv | AT adekanmbiolukemi characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT ilesanmiolayinka characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT idowuolusola characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT esanarinola characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT rajiyemir characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT fowotadeadeola characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT ogunladeolubunmi characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT akereadegboyega characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT ololadeoluwaseun characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT ojifinnikehinde characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT akinolaolurotimi characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT orunmuyiakintunde characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT ezeuwom characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT akinmoladunvictor characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT adeoyeabiodun characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT adebiyiakindele characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT olapadeolaopaeoluwabunmi characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT otegbayojessea characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria AT osungbadekayode characteristicsandoutcomesofpatientshospitalizedwithcovid19atatertiaryhospitalinnigeria |