DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression

Cortical neurogenesis depends on the balance between self‐renewal and differentiation of apical progenitors (APs). Here, we study the epigenetic control of AP's division mode by focusing on the enzymatic activity of the histone methyltransferase DOT1L. Combining lineage tracing with single‐cell...

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Detalles Bibliográficos
Autores principales: Appiah, Bismark, Fullio, Camila L, Ossola, Chiara, Bertani, Ilaria, Restelli, Elena, Cheffer, Arquimedes, Polenghi, Martina, Haffner, Christiane, Garcia‐Miralles, Marta, Zeis, Patrice, Treppner, Martin, Bovio, Patrick, Schlichtholz, Laura, Mas‐Sanchez, Aina, Zografidou, Lea, Winter, Jennifer, Binder, Harald, Grün, Dominic, Kalebic, Nereo, Taverna, Elena, Vogel, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398646/
https://www.ncbi.nlm.nih.gov/pubmed/37382163
http://dx.doi.org/10.15252/embr.202256233

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