ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein

Abnormal tau protein impairs mitochondrial function, including transport, dynamics, and bioenergetics. Mitochondria interact with the endoplasmic reticulum (ER) via mitochondria‐associated ER membranes (MAMs), which coordinate and modulate many cellular functions, including mitochondrial cholesterol...

Descripción completa

Detalles Bibliográficos
Autores principales: Szabo, Leonora, Cummins, Nadia, Paganetti, Paolo, Odermatt, Alex, Papassotiropoulos, Andreas, Karch, Celeste, Götz, Jürgen, Eckert, Anne, Grimm, Amandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398652/
https://www.ncbi.nlm.nih.gov/pubmed/37401859
http://dx.doi.org/10.15252/embr.202357499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398652/
https://www.ncbi.nlm.nih.gov/pubmed/37401859
http://dx.doi.org/10.15252/embr.202357499

Ejemplares similares