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Therapeutic Potential of Methotrexate-Loaded Superparamagnetic Iron Oxide Nanoparticles Coated with Poly(lactic-co-glycolic acid) and Polyethylene Glycol against Breast Cancer: Development, Characterization, and Comprehensive In Vitro Investigation
[Image: see text] Novel superparamagnetic iron oxide nanoparticles (SPIONs) of Methotrexate (MTX) were developed using supercritical liquid technology and optimized with a Box–Behnken design in order to assess its potential as a candidate for the treatment of breast cancer. MTX-SPIONs coated with po...
Autores principales: | Bhattacharya, Sankha, Prajapati, Bhupendra G, Ali, Nemat, Mohany, Mohamed, Aboul-Soud, Mourad A. M., Khan, Rehan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398847/ https://www.ncbi.nlm.nih.gov/pubmed/37546601 http://dx.doi.org/10.1021/acsomega.3c03430 |
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