Cargando…
Discovery of Hybrid Thiouracil–Coumarin Conjugates as Potential Novel Anti-SARS-CoV-2 Agents Targeting the Virus’s Polymerase “RdRp” as a Confirmed Interacting Biomolecule
[Image: see text] The coronavirus (COVID-19) pandemic, along with its various strains, has emerged as a global health crisis that has severely affected humankind and posed a great challenge to the public health system of affected countries. The replication of severe acute respiratory syndrome corona...
Autores principales: | Vishwanath, Divakar, Shete-Aich, Anita, Honnegowda, Manjunath B., Anand, Mahesh Padukudru, Chidambaram, Saravana Babu, Sapkal, Gajanan, Basappa, Basappa, Yadav, Pragya D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398856/ https://www.ncbi.nlm.nih.gov/pubmed/37546653 http://dx.doi.org/10.1021/acsomega.3c02079 |
Ejemplares similares
-
Electrochemical Synthesis of New Isoxazoles and Triazoles Tethered with Thiouracil Base as Inhibitors of Histone Deacetylases in Human Breast Cancer Cells
por: Vishwanath, Divakar, et al.
Publicado: (2023) -
Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells
por: Kim, Na Young, et al.
Publicado: (2023) -
RdRp or RT, That is the Question
por: Peyambari, Mahtab, et al.
Publicado: (2021) -
Biomolecules of 2-Thiouracil, 4-Thiouracil and 2,4-Dithiouracil: A DFT Study of the Hydration, Molecular Docking and Effect in DNA:RNAMicrohelixes
por: Alcolea Palafox, M., et al.
Publicado: (2019) -
Snapshots of a Non-Canonical RdRP in Action
por: Ferrero, Diego S., et al.
Publicado: (2021)