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Simultaneous Hydrodistillation of Cedrus atlantica Manetti and Salvia rosmarinus Spenn: Optimization of Anti-Wood-Decay Fungal Activity Using Mixture Design Methodology

[Image: see text] Chemical fungicides are often harmful to people and the environment because of their toxicity. The wood protection industry places a high priority on replacing them with natural products. Therefore, this investigation focused on developing a formulation of a binary combination of S...

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Detalles Bibliográficos
Autores principales: Annemer, Saoussan, Ez zoubi, Yassine, Satrani, Badr, Stambouli, Hamid, Assouguem, Amine, Ullah, Riaz, Ali, Essam A., Ercisli, Sezai, Marc, Romina Alina, Bouayoun, Taoufik, Farah, Abdellah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398857/
https://www.ncbi.nlm.nih.gov/pubmed/37546586
http://dx.doi.org/10.1021/acsomega.3c01970
Descripción
Sumario:[Image: see text] Chemical fungicides are often harmful to people and the environment because of their toxicity. The wood protection industry places a high priority on replacing them with natural products. Therefore, this investigation focused on developing a formulation of a binary combination of Salvia rosmarinus Spenn and Cedrus atlantica Manetti obtained by Simultaneous hydrodistillation to protect the wood from decay using a mixture design methodology. The chemical composition of essential oil was identified by gas chromatography coupled with mass spectrometry (GC/MS), and their anti-wood-decay fungal activity was assessed using the macrodilution method against four fungi responsible for wood decay: Coniophora puteana, Coriolus versicolor, Gloeophyllum trabeum, and Poria placenta. The results of GC/MS identified myrtenal as a new component appearing in all binary combinations. The optimum anti-wood-decay fungal activity was observed in a combination of 60% S. rosmarinus and 40% C. atlantica essential oils, providing an effective concentration for 50% of maximal effect (EC(50)) value of 9.91 ± 1.91 and 9.28 ± 1.55 μg/mL for C. puteana and C. versicolor, respectively. The highest anti-wood-decay fungal activity for G. trabeum and P. placenta was found in the combination of 55% of S. rosmarinus and 45% of C. atlantica essential oils, with EC(50) values of 11.48 ± 3.73 and 22.619 ± 3.79 μg/mL, respectively. Combined simultaneous hydrodistillation improved the antifungal effect of these essential oils. These results could be used to improve antifungal activity and protect wood against wood-decay fungi.