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High extracellular glucose promotes cell motility by modulating cell deformability and contractility via the cAMP-RhoA-ROCK axis in human breast cancer cells

The mechanical properties, or mechanotypes, of cells are largely determined by their deformability and contractility. The ability of cancer cells to deform and generate contractile force is critical in multiple steps of metastasis. Identifying soluble cues that regulate cancer cell mechanotypes and...

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Detalles Bibliográficos
Autores principales: Oh, Mijung, Batty, Skylar, Banerjee, Nayan, Kim, Tae-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398875/
https://www.ncbi.nlm.nih.gov/pubmed/37195739
http://dx.doi.org/10.1091/mbc.E22-12-0560