Cargando…
Efficient fusion requires a membrane anchor on the vacuolar Qa-SNARE
As a prelude to fusion, the R-SNARE on one membrane zippers with Qa-, Qb-, and Qc-SNAREs from its apposed fusion partner, forming a four-helical bundle that draws the two membranes together. Because Qa- and Qb-SNAREs are anchored to the same membrane and are adjacent in the 4-SNARE bundle, their two...
Autores principales: | Wickner, William, Lopes, Karina, Song, Hongki, Rizo, Josep, Orr, Amy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398888/ https://www.ncbi.nlm.nih.gov/pubmed/37314849 http://dx.doi.org/10.1091/mbc.E23-02-0052 |
Ejemplares similares
-
A short region upstream of the yeast vacuolar Qa-SNARE heptad-repeats promotes membrane fusion through enhanced SNARE complex assembly
por: Song, Hongki, et al.
Publicado: (2017) -
Fusion with wild-type SNARE domains is controlled by juxtamembrane domains, transmembrane anchors, and Sec17
por: Orr, Amy, et al.
Publicado: (2022) -
HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex
por: Orr, Amy, et al.
Publicado: (2017) -
Asymmetric Rab activation of vacuolar HOPS to catalyze SNARE complex assembly
por: Torng, Thomas, et al.
Publicado: (2020) -
Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes
por: Song, Hongki, et al.
Publicado: (2017)