Prmt5 deficiency inhibits CD4+ T-cell Klf2/S1pr1 expression and ameliorates EAE disease

BACKGROUND: Protein arginine methyltransferase 5 (Prmt5) is the main type II methyltransferase, catalyzes protein arginine residue symmetric dimethylation, and modulates normal cellular physiology and disease progression. Prmt5 inhibition or deletion in CD4+ T cells has been reported to ameliorate e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yingxia, Chen, Zheyi, Zhou, Bingqian, Chen, Shiyu, Chen, Ningdai, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398933/
https://www.ncbi.nlm.nih.gov/pubmed/37533053
http://dx.doi.org/10.1186/s12974-023-02854-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398933/
https://www.ncbi.nlm.nih.gov/pubmed/37533053
http://dx.doi.org/10.1186/s12974-023-02854-2

Ejemplares similares