Predicting delayed methotrexate elimination in pediatric acute lymphoblastic leukemia patients: an innovative web-based machine learning tool developed through a multicenter, retrospective analysis

BACKGROUND: High-dose methotrexate (HD-MTX) is a potent chemotherapeutic agent used to treat pediatric acute lymphoblastic leukemia (ALL). HD-MTX is known for cause delayed elimination and drug-related adverse events. Therefore, close monitoring of delayed MTX elimination in ALL patients is essentia...

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Detalles Bibliográficos
Autores principales: Jian, Chang, Chen, Siqi, Wang, Zhuangcheng, Zhou, Yang, Zhang, Yang, Li, Ziyu, Jian, Jie, Wang, Tingting, Xiang, Tianyu, Wang, Xiao, Jia, Yuntao, Wang, Huilai, Gong, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398990/
https://www.ncbi.nlm.nih.gov/pubmed/37537590
http://dx.doi.org/10.1186/s12911-023-02248-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398990/
https://www.ncbi.nlm.nih.gov/pubmed/37537590
http://dx.doi.org/10.1186/s12911-023-02248-7

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