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Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers
BACKGROUND: DNA hypermethylation is an epigenetic feature that modulates gene expression, and its deregulation is observed in cancer. Previously, we identified a neural-related DNA hypermethylation fingerprint in colon cancer, where most of the top hypermethylated and downregulated genes have known...
Autores principales: | Idris, Musa, Coussement, Louis, Alves, Maria M., De Meyer, Tim, Melotte, Veerle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398991/ https://www.ncbi.nlm.nih.gov/pubmed/37537688 http://dx.doi.org/10.1186/s13072-023-00505-7 |
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