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Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers

BACKGROUND: DNA hypermethylation is an epigenetic feature that modulates gene expression, and its deregulation is observed in cancer. Previously, we identified a neural-related DNA hypermethylation fingerprint in colon cancer, where most of the top hypermethylated and downregulated genes have known...

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Detalles Bibliográficos
Autores principales:	Idris, Musa, Coussement, Louis, Alves, Maria M., De Meyer, Tim, Melotte, Veerle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398991/ https://www.ncbi.nlm.nih.gov/pubmed/37537688 http://dx.doi.org/10.1186/s13072-023-00505-7

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