APP family member dimeric complexes are formed predominantly in synaptic compartments

BACKGROUND: The amyloid precursor protein (APP), a key player in Alzheimer’s disease (AD), is part of a larger gene family, including the APP like proteins APLP1 and APLP2. They share similar structures, form homo- and heterotypic dimers and exhibit overlapping functions. RESULTS: We investigated co...

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Detalles Bibliográficos
Autores principales: Schilling, Sandra, August, Alexander, Meleux, Mathieu, Conradt, Carolin, Tremmel, Luisa M., Teigler, Sandra, Adam, Virginie, Müller, Ulrike C., Koo, Edward H., Kins, Stefan, Eggert, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398996/
https://www.ncbi.nlm.nih.gov/pubmed/37533067
http://dx.doi.org/10.1186/s13578-023-01092-6

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