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Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature
BACKGROUND: Solitary fibrous tumors (SFTs) are very rare spindle cell neoplasms of mesenchymal origin with largely benign course of disease. Genital SFT’s can be managed providing excellent functional and psychological outcomes by timely intervention. CASE PRESENTATION: We report the largest and pos...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399031/ https://www.ncbi.nlm.nih.gov/pubmed/37533000 http://dx.doi.org/10.1186/s12894-023-01302-w |
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author | Jain, Deep Kumar Pandey, Himanshu Saini, Sashank Patne, Sashikant |
author_facet | Jain, Deep Kumar Pandey, Himanshu Saini, Sashank Patne, Sashikant |
author_sort | Jain, Deep Kumar |
collection | PubMed |
description | BACKGROUND: Solitary fibrous tumors (SFTs) are very rare spindle cell neoplasms of mesenchymal origin with largely benign course of disease. Genital SFT’s can be managed providing excellent functional and psychological outcomes by timely intervention. CASE PRESENTATION: We report the largest and possibly the second only reported case of penile SFT in a 34 year male presenting with a gradually increasing perineal mass with clinically normal appearing phallus. MRI revealed a 9.8 × 3.2 cm soft tissue mass arising from left corpora cavernosae, the mass was excised en-bloc via a perineal approach under spinal anaesthesia. Histopathology revealed spindle cell tumor embedded in myxohyaline stroma along with hyalinized vascular channels demonstrating IHC positivity for CD34 and STAT6. The patient is disease free post 2 years of resection with no sexual or urinary dysfunctions. CONCLUSION: Genital SFTs, although rare, should be considered in the differential diagnosis of well-circumscribed, painless, slow growing solid masses and histopathologists must be vigilant of its malignant characteristics. |
format | Online Article Text |
id | pubmed-10399031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103990312023-08-04 Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature Jain, Deep Kumar Pandey, Himanshu Saini, Sashank Patne, Sashikant BMC Urol Case Report BACKGROUND: Solitary fibrous tumors (SFTs) are very rare spindle cell neoplasms of mesenchymal origin with largely benign course of disease. Genital SFT’s can be managed providing excellent functional and psychological outcomes by timely intervention. CASE PRESENTATION: We report the largest and possibly the second only reported case of penile SFT in a 34 year male presenting with a gradually increasing perineal mass with clinically normal appearing phallus. MRI revealed a 9.8 × 3.2 cm soft tissue mass arising from left corpora cavernosae, the mass was excised en-bloc via a perineal approach under spinal anaesthesia. Histopathology revealed spindle cell tumor embedded in myxohyaline stroma along with hyalinized vascular channels demonstrating IHC positivity for CD34 and STAT6. The patient is disease free post 2 years of resection with no sexual or urinary dysfunctions. CONCLUSION: Genital SFTs, although rare, should be considered in the differential diagnosis of well-circumscribed, painless, slow growing solid masses and histopathologists must be vigilant of its malignant characteristics. BioMed Central 2023-08-02 /pmc/articles/PMC10399031/ /pubmed/37533000 http://dx.doi.org/10.1186/s12894-023-01302-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Jain, Deep Kumar Pandey, Himanshu Saini, Sashank Patne, Sashikant Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title | Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title_full | Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title_fullStr | Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title_full_unstemmed | Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title_short | Large Solitary Fibrous Tumor (SFT) of the penis- a case report and review of literature |
title_sort | large solitary fibrous tumor (sft) of the penis- a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399031/ https://www.ncbi.nlm.nih.gov/pubmed/37533000 http://dx.doi.org/10.1186/s12894-023-01302-w |
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