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ATRA sensitized the response of hepatocellular carcinoma to Sorafenib by downregulation of p21-activated kinase 1

BACKGROUND: Sorafenib resistance greatly reduces the efficacy of treatments in advanced hepatocellular carcinoma (HCC) patients, but the underlying mechanisms are not thoroughly understood. All-trans retinoic acid (ATRA), an anti-leukaemia agent, has attracted considerable attention due to its role...

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Detalles Bibliográficos
Autores principales:	Wang, Kai, Qiu, Xun, Zhang, Zhensheng, Xu, Hanzhi, Tan, Yawen, Su, Renyi, Gao, Fengqiang, Zhuo, Jianyong, Li, Wangyao, Lian, Zhengxing, He, Hong, Xu, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399044/ https://www.ncbi.nlm.nih.gov/pubmed/37537668 http://dx.doi.org/10.1186/s12964-023-01194-1

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