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Insights into Enzymatic Catalysis from Binding and Hydrolysis of Diadenosine Tetraphosphate by E. coli Adenylate Kinase
[Image: see text] Adenylate kinases play a crucial role in cellular energy homeostasis through the interconversion of ATP, AMP, and ADP in all living organisms. Here, we explore how adenylate kinase (AdK) from Escherichia coli interacts with diadenosine tetraphosphate (AP4A), a putative alarmone ass...
Autores principales: | Tischlik, Sonja, Oelker, Melanie, Rogne, Per, Sauer-Eriksson, A. Elisabeth, Drescher, Malte, Wolf-Watz, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399197/ https://www.ncbi.nlm.nih.gov/pubmed/37418448 http://dx.doi.org/10.1021/acs.biochem.3c00189 |
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