Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery

Introduction: The availability of large-scale biobanks linking genetic data, rich phenotypes, and biological measures is a powerful opportunity for scientific discovery. However, real-world collections frequently have extensive missingness. While missing data prediction is possible, performance is s...

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Detalles Bibliográficos
Autores principales: Gentry, Amanda Elswick, Kirkpatrick, Robert M., Peterson, Roseann E., Webb, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399453/
https://www.ncbi.nlm.nih.gov/pubmed/37547462
http://dx.doi.org/10.3389/fgene.2023.1162690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399453/
https://www.ncbi.nlm.nih.gov/pubmed/37547462
http://dx.doi.org/10.3389/fgene.2023.1162690

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