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Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions

The RhoGEF Trio is a large multi-domain protein and an activator of the small GTPases Rac1, RhoG, and RhoA. Although Trio has been implicated in many cellular mechanisms like leukocyte transendothelial migration, cell-cell junction stability, lamellipodia formation, axon outgrowth, and muscle fusion...

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Detalles Bibliográficos
Autores principales: Daniel, Anna E., van der Meer, Werner J., Wester, Lynn, de Waard, Vivian, van den Biggelaar, Maartje, van Buul, Jaap D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399470/
https://www.ncbi.nlm.nih.gov/pubmed/37528624
http://dx.doi.org/10.1080/21541248.2023.2242166