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Pre-mRNA splicing-associated diseases and therapies

Precursor mRNA (pre-mRNA) splicing is an essential step in human gene expression and is carried out by a large macromolecular machine called the spliceosome. Given the spliceosome's role in shaping the cellular transcriptome, it is not surprising that mutations in the splicing machinery can res...

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Detalles Bibliográficos
Autores principales:	Love, Sierra L., Emerson, Joseph D., Koide, Kazunori, Hoskins, Aaron A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399480/ https://www.ncbi.nlm.nih.gov/pubmed/37528617 http://dx.doi.org/10.1080/15476286.2023.2239601

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