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Inhibition of MC38 colon cancer growth by multicomponent chemoimmunotherapy with anti-IL-10R antibodies, HES-MTX nanoconjugate, depends on application of IL-12, IL-15 or IL-18 secreting dendritic cell vaccines

BACKGROUND: The tumor microenvironment (TME) provides a conducive environment for the growth and survival of tumors. Negative factors present in TME, such as IL-10, may limit the effectiveness of cellular vaccines based on dendritic cells, therefore, it is important to control its effect. The influe...

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Detalles Bibliográficos
Autores principales:	Węgierek-Ciura, Katarzyna, Mierzejewska, Jagoda, Szczygieł, Agnieszka, Rossowska, Joanna, Wróblewska, Anna, Świtalska, Marta, Goszczyński, Tomasz M., Szermer-Olearnik, Bożena, Pajtasz-Piasecka, Elżbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399586/ https://www.ncbi.nlm.nih.gov/pubmed/37545526 http://dx.doi.org/10.3389/fimmu.2023.1212606

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