A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy

Penile cancer is a rare cancer in developed nations, with metastatic disease seen in under 10% of cases at presentation. Treatment is multimodal and dependent on tumor stage, risk of recurrence, nodal involvement, and advancement of the disease. We report a case of a 49-year-old male with penile squ...

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Detalles Bibliográficos
Autores principales: Zong, Perry, Garlapati, Jay, Miller, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399608/
https://www.ncbi.nlm.nih.gov/pubmed/37546144
http://dx.doi.org/10.7759/cureus.41358
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author Zong, Perry
Garlapati, Jay
Miller, Steven
author_facet Zong, Perry
Garlapati, Jay
Miller, Steven
author_sort Zong, Perry
collection PubMed
description Penile cancer is a rare cancer in developed nations, with metastatic disease seen in under 10% of cases at presentation. Treatment is multimodal and dependent on tumor stage, risk of recurrence, nodal involvement, and advancement of the disease. We report a case of a 49-year-old male with penile squamous cell carcinoma, who initially presented with a penile lesion but became lost to follow-up due to the coronavirus disease 2019 (COVID-19) pandemic. Therapies included surgical resection, chemotherapy, and external beam radiation therapy. His disease course was additionally complicated by its aggressive nature, poor response to first-line chemotherapy, and secondary nosocomial infections. 
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spelling pubmed-103996082023-08-04 A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy Zong, Perry Garlapati, Jay Miller, Steven Cureus Radiation Oncology Penile cancer is a rare cancer in developed nations, with metastatic disease seen in under 10% of cases at presentation. Treatment is multimodal and dependent on tumor stage, risk of recurrence, nodal involvement, and advancement of the disease. We report a case of a 49-year-old male with penile squamous cell carcinoma, who initially presented with a penile lesion but became lost to follow-up due to the coronavirus disease 2019 (COVID-19) pandemic. Therapies included surgical resection, chemotherapy, and external beam radiation therapy. His disease course was additionally complicated by its aggressive nature, poor response to first-line chemotherapy, and secondary nosocomial infections.  Cureus 2023-07-04 /pmc/articles/PMC10399608/ /pubmed/37546144 http://dx.doi.org/10.7759/cureus.41358 Text en Copyright © 2023, Zong et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Zong, Perry
Garlapati, Jay
Miller, Steven
A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title_full A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title_fullStr A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title_full_unstemmed A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title_short A Case Report of Refractory Penile Squamous Cell Carcinoma Treated With Surgical Resection, Chemotherapy and External Beam Radiation Therapy
title_sort case report of refractory penile squamous cell carcinoma treated with surgical resection, chemotherapy and external beam radiation therapy
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399608/
https://www.ncbi.nlm.nih.gov/pubmed/37546144
http://dx.doi.org/10.7759/cureus.41358
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