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Improved detection of homologous recombination deficiency in Chinese patients with ovarian cancer: a novel non‐exonic single‐nucleotide polymorphism‐based next‐generation sequencing panel

As homologous recombination deficiency (HRD) is a biomarker to predict the efficiency of PARP inhibitor treatment, this study developed a non‐exonic single‐nucleotide polymorphism (SNP)‐based targeted next‐generation sequencing panel and comprehensively examined it both on standard and clinical ovar...

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Detalles Bibliográficos
Autores principales: Wei, Bing, Zheng, Jinxiang, Jiang, Cai, Zhang, He, Zhang, Mingye, Cheng, Taoran, Li, Jun, Wang, Zhizhong, Deng, Lijun, Wang, Li, Xia, Qingxin, Ma, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399708/
https://www.ncbi.nlm.nih.gov/pubmed/36852736
http://dx.doi.org/10.1002/1878-0261.13411