Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids

Control of tumour development and growth by the immune system critically defines patient fate and survival. What regulates the escape of colorectal tumours from destruction by the immune system remains currently unclear. Here, we investigated the role of intestinal synthesis of glucocorticoids in th...

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Detalles Bibliográficos
Autores principales: Ahmed, Asma, Reinhold, Cindy, Breunig, Eileen, Phan, Truong San, Dietrich, Lea, Kostadinova, Feodora, Urwyler, Corinne, Merk, Verena M., Noti, Mario, Toja da Silva, Israel, Bode, Konstantin, Nahle, Fatima, Plazzo, Anna Pia, Koerner, Julia, Stuber, Regula, Menche, Constantin, Karamitopoulou, Eva, Farin, Henner F., Gollob, Kenneth J., Brunner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399709/
https://www.ncbi.nlm.nih.gov/pubmed/36861295
http://dx.doi.org/10.1002/1878-0261.13414

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