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Divide, conquer and reconstruct: How to solve the 3D structure of recalcitrant Micro-Exon Gene (MEG) protein from Schistosoma mansoni

Micro-Exon Genes are a widespread class of genes known for their high variability, widespread in the genome of parasitic trematodes such as Schistosoma mansoni. In this study, we present a strategy that allowed us to solve the structures of three alternatively spliced isoforms from the Schistoma man...

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Detalles Bibliográficos
Autores principales: Nedvedova, Stepanka, Guillière, Florence, Miele, Adriana Erica, Cantrelle, François-Xavier, Dvorak, Jan, Walker, Olivier, Hologne, Maggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399815/
https://www.ncbi.nlm.nih.gov/pubmed/37535563
http://dx.doi.org/10.1371/journal.pone.0289444