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Micelle-like clusters in phase-separated Nanog condensates: A molecular simulation study

The phase separation model for transcription suggests that transcription factors (TFs), coactivators, and RNA polymerases form biomolecular condensates around active gene loci and regulate transcription. However, the structural details of condensates remain elusive. In this study, for Nanog, a maste...

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Detalles Bibliográficos
Autores principales: Mizutani, Azuki, Tan, Cheng, Sugita, Yuji, Takada, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399900/
https://www.ncbi.nlm.nih.gov/pubmed/37486948
http://dx.doi.org/10.1371/journal.pcbi.1011321