Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2, and CYP2C9 variants

The association of SLCO1B1 c.521T>C with simvastatin-induced muscle toxicity is well characterized. However, different statins are subject to metabolism and transport also by other proteins exhibiting clinically meaningful genetic variation. Our aim was to investigate associations of SLCO1B1 c.52...

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Detalles Bibliográficos
Autores principales: Lönnberg, K. Ivar, Tornio, Aleksi, Hirvensalo, Päivi, Keskitalo, Jenni, Mustaniemi, Anna-Liina, Kiiski, Johanna I., Filppula, Anne M., Niemi, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399933/
https://www.ncbi.nlm.nih.gov/pubmed/37490620
http://dx.doi.org/10.1097/FPC.0000000000000504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399933/
https://www.ncbi.nlm.nih.gov/pubmed/37490620
http://dx.doi.org/10.1097/FPC.0000000000000504

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