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Older age bipolar disorder

Older age bipolar disorder (OABD) refers to patients with bipolar disorder aged 50 years and over. There is a paucity of evidence-based guidelines specific to OABD, but in recent years, several studies have been published on OABD. The current review synthesizes previous literature (up to January 1,...

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Autores principales: Beunders, Alexandra J.M., Orhan, Melis, Dols, Annemiek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399956/
https://www.ncbi.nlm.nih.gov/pubmed/37458495
http://dx.doi.org/10.1097/YCO.0000000000000883
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author Beunders, Alexandra J.M.
Orhan, Melis
Dols, Annemiek
author_facet Beunders, Alexandra J.M.
Orhan, Melis
Dols, Annemiek
author_sort Beunders, Alexandra J.M.
collection PubMed
description Older age bipolar disorder (OABD) refers to patients with bipolar disorder aged 50 years and over. There is a paucity of evidence-based guidelines specific to OABD, but in recent years, several studies have been published on OABD. The current review synthesizes previous literature (up to January 1, 2021) as well as most recent literature on OABD (since January 1, 2021). RECENT FINDINGS: This review covers the following themes: diagnosis and specifiers, clinical course, psychosocial functioning, cognition, physical comorbidities, and pharmacotherapy. On the basis of the latest data, specific clinical recommendations are proposed for each theme. SUMMARY: OABD forms a more complex subgroup of bipolar disorder, with an increased risk of cognitive deficits, physical comorbidities, impaired psychosocial functioning, and premature death. The distinctions between BD-I and BD-II and between EOBD and LOBD do not clinically represent relevant subtypes for OABD patients. Mental healthcare professionals should treat all OABD patients with an integrative care model that takes into account cognitive and physical comorbidities and that contains elements aimed at improvement of psychosocial functioning and quality of life. Older age itself should not be a reason to withhold lithium treatment. Future research should collect data on essential data domains using validated measurement scales.
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spelling pubmed-103999562023-08-04 Older age bipolar disorder Beunders, Alexandra J.M. Orhan, Melis Dols, Annemiek Curr Opin Psychiatry GERIATRIC PSYCHIATRY: Edited by Orestes Forlenza and Claudia Cooper Older age bipolar disorder (OABD) refers to patients with bipolar disorder aged 50 years and over. There is a paucity of evidence-based guidelines specific to OABD, but in recent years, several studies have been published on OABD. The current review synthesizes previous literature (up to January 1, 2021) as well as most recent literature on OABD (since January 1, 2021). RECENT FINDINGS: This review covers the following themes: diagnosis and specifiers, clinical course, psychosocial functioning, cognition, physical comorbidities, and pharmacotherapy. On the basis of the latest data, specific clinical recommendations are proposed for each theme. SUMMARY: OABD forms a more complex subgroup of bipolar disorder, with an increased risk of cognitive deficits, physical comorbidities, impaired psychosocial functioning, and premature death. The distinctions between BD-I and BD-II and between EOBD and LOBD do not clinically represent relevant subtypes for OABD patients. Mental healthcare professionals should treat all OABD patients with an integrative care model that takes into account cognitive and physical comorbidities and that contains elements aimed at improvement of psychosocial functioning and quality of life. Older age itself should not be a reason to withhold lithium treatment. Future research should collect data on essential data domains using validated measurement scales. Lippincott Williams & Wilkins 2023-09 2023-07-17 /pmc/articles/PMC10399956/ /pubmed/37458495 http://dx.doi.org/10.1097/YCO.0000000000000883 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle GERIATRIC PSYCHIATRY: Edited by Orestes Forlenza and Claudia Cooper
Beunders, Alexandra J.M.
Orhan, Melis
Dols, Annemiek
Older age bipolar disorder
title Older age bipolar disorder
title_full Older age bipolar disorder
title_fullStr Older age bipolar disorder
title_full_unstemmed Older age bipolar disorder
title_short Older age bipolar disorder
title_sort older age bipolar disorder
topic GERIATRIC PSYCHIATRY: Edited by Orestes Forlenza and Claudia Cooper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399956/
https://www.ncbi.nlm.nih.gov/pubmed/37458495
http://dx.doi.org/10.1097/YCO.0000000000000883
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