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The ototoxic drug cisplatin localises to stress granules altering their dynamics and composition
Cisplatin is an effective platinum-based chemotherapeutic with several side effects, including ototoxicity. Cochlear cells have low rates of proliferation yet are highly susceptible to cisplatin. We hypothesised that cisplatin ototoxicity might be caused by cisplatin–protein interactions rather than...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10399988/ https://www.ncbi.nlm.nih.gov/pubmed/37334742 http://dx.doi.org/10.1242/jcs.260590 |