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Impact of in vitro HIV infection on human thymic regulatory T cell differentiation

BACKGROUND: The differentiation and function of immunosuppressive regulatory T cells (Tregs) is dictated by the master transcription factor FoxP3. During HIV infection, there is an increase in Treg frequencies in the peripheral blood and lymphoid tissues. This accentuates immune dysfunction and dise...

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Detalles Bibliográficos
Autores principales: Swaminathan, Sharada, Scorza, Tatiana, Yero, Alexis, Farnos, Omar, Burke Schinkel, Stephanie C., Angel, Jonathan B., Jenabian, Mohammad-Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400333/
https://www.ncbi.nlm.nih.gov/pubmed/37547675
http://dx.doi.org/10.3389/fmicb.2023.1217801