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Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review
A 46-year-old man was referred to our hospital for the examination of a flat elevated lesion with an erosion-like depression, located on the greater curvature of the antrum. Endoscopic submucosal dissection was performed. Histological findings of the resected specimen demonstrated a well-differentia...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400381/ https://www.ncbi.nlm.nih.gov/pubmed/36450460 http://dx.doi.org/10.2169/internalmedicine.0246-22 |
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author | Murawaki, Yoshiyuki Yashima, Kazuo Horie, Satoshi Miura, Masahiko Kato, Jun Hirai, Takayuki Takeda, Kazuki Kono, Michimori Yoshida, Manabu Isomoto, Hajime |
author_facet | Murawaki, Yoshiyuki Yashima, Kazuo Horie, Satoshi Miura, Masahiko Kato, Jun Hirai, Takayuki Takeda, Kazuki Kono, Michimori Yoshida, Manabu Isomoto, Hajime |
author_sort | Murawaki, Yoshiyuki |
collection | PubMed |
description | A 46-year-old man was referred to our hospital for the examination of a flat elevated lesion with an erosion-like depression, located on the greater curvature of the antrum. Endoscopic submucosal dissection was performed. Histological findings of the resected specimen demonstrated a well-differentiated tubular adenocarcinoma with a diameter of 12 mm. No atrophy was observed in the tumor-adjacent mucosa. Serum Helicobacter pylori antibody estimation and (13)C-urea breath tests yielded negative results. Immunohistochemical staining was positive for both gastric mucin and intestinal mucin. The final diagnosis was well-differentiated tubular adenocarcinoma with a gastrointestinal phenotype that originated in mucosa uninfected by H. pylori. |
format | Online Article Text |
id | pubmed-10400381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-104003812023-08-05 Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review Murawaki, Yoshiyuki Yashima, Kazuo Horie, Satoshi Miura, Masahiko Kato, Jun Hirai, Takayuki Takeda, Kazuki Kono, Michimori Yoshida, Manabu Isomoto, Hajime Intern Med Case Report A 46-year-old man was referred to our hospital for the examination of a flat elevated lesion with an erosion-like depression, located on the greater curvature of the antrum. Endoscopic submucosal dissection was performed. Histological findings of the resected specimen demonstrated a well-differentiated tubular adenocarcinoma with a diameter of 12 mm. No atrophy was observed in the tumor-adjacent mucosa. Serum Helicobacter pylori antibody estimation and (13)C-urea breath tests yielded negative results. Immunohistochemical staining was positive for both gastric mucin and intestinal mucin. The final diagnosis was well-differentiated tubular adenocarcinoma with a gastrointestinal phenotype that originated in mucosa uninfected by H. pylori. The Japanese Society of Internal Medicine 2022-11-30 2023-07-15 /pmc/articles/PMC10400381/ /pubmed/36450460 http://dx.doi.org/10.2169/internalmedicine.0246-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Murawaki, Yoshiyuki Yashima, Kazuo Horie, Satoshi Miura, Masahiko Kato, Jun Hirai, Takayuki Takeda, Kazuki Kono, Michimori Yoshida, Manabu Isomoto, Hajime Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title |
Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title_full |
Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title_fullStr |
Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title_full_unstemmed |
Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title_short |
Helicobacter pylori-negative Gastric Adenocarcinoma Mimicking Verrucous Gastritis in the Antrum: A Case Report and Literature Review |
title_sort | helicobacter pylori-negative gastric adenocarcinoma mimicking verrucous gastritis in the antrum: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400381/ https://www.ncbi.nlm.nih.gov/pubmed/36450460 http://dx.doi.org/10.2169/internalmedicine.0246-22 |
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