Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model

Imiquimod (IMQ) is a topical agent that induces local inflammation via the Toll-like receptor 7 pathway. Recently, an IMQ-driven skin inflammation model was developed in healthy volunteers for proof-of-pharmacology trials. The aim of this study was to profile the cellular, biochemical, and clinical...

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Detalles Bibliográficos
Autores principales: Assil, Salma, Buters, Thomas P., Hameeteman, Pieter W., Hallard, Charlie, Treijtel, Nicoline, Niemeyer – Van der Kolk, Tessa, de Kam, Marieke L., Florencia, Edwin F. I. I. I., Prens, Errol P., van Doorn, Martijn B. A., Rissmann, Robert, Klarenbeek, Naomi B., Jansen, Manon A. A., Moerland, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400434/
https://www.ncbi.nlm.nih.gov/pubmed/37545524
http://dx.doi.org/10.3389/fimmu.2023.1197650

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