5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expression

The effective treatment of breast cancer remains a profound clinical challenge, especially due to drug resistance and metastasis which unfortunately arise in many patients. The transcription inhibitor 5,6-dichloro-1-beta-D-ribofuranosyl-benzimidazole (DRB), as a selective inhibitor of cyclin-depende...

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Detalles Bibliográficos
Autores principales: Kuo, Yi-Hsuan, Lai, Tsai-Chun, Chang, Chia-Hsin, Hsieh, Han-Ching, Yang, Feng-Ming, Hu, Meng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400577/
https://www.ncbi.nlm.nih.gov/pubmed/37537243
http://dx.doi.org/10.1038/s41598-023-39340-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400577/
https://www.ncbi.nlm.nih.gov/pubmed/37537243
http://dx.doi.org/10.1038/s41598-023-39340-x

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