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5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expression
The effective treatment of breast cancer remains a profound clinical challenge, especially due to drug resistance and metastasis which unfortunately arise in many patients. The transcription inhibitor 5,6-dichloro-1-beta-D-ribofuranosyl-benzimidazole (DRB), as a selective inhibitor of cyclin-depende...
Autores principales: | Kuo, Yi-Hsuan, Lai, Tsai-Chun, Chang, Chia-Hsin, Hsieh, Han-Ching, Yang, Feng-Ming, Hu, Meng-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400577/ https://www.ncbi.nlm.nih.gov/pubmed/37537243 http://dx.doi.org/10.1038/s41598-023-39340-x |
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