Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model

Traumatic Brain injury-induced disturbances in mitochondrial fission-and-fusion dynamics have been linked to the onset and propagation of neuroinflammation and neurodegeneration. However, cell-type-specific contributions and crosstalk between neurons, microglia, and astrocytes in mitochondria-driven...

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Detalles Bibliográficos
Autores principales: Liaudanskaya, Volha, Fiore, Nicholas J., Zhang, Yang, Milton, Yuka, Kelly, Marilyn F., Coe, Marly, Barreiro, Ariana, Rose, Victoria K., Shapiro, Matthew R., Mullis, Adam S., Shevzov-Zebrun, Anna, Blurton-Jones, Mathew, Whalen, Michael J., Symes, Aviva J., Georgakoudi, Irene, Nieland, Thomas J. F., Kaplan, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400598/
https://www.ncbi.nlm.nih.gov/pubmed/37537168
http://dx.doi.org/10.1038/s41419-023-05980-0

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