MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation

Chikungunya virus (CHIKV) infection has been associated with severe cardiac manifestations, yet, how CHIKV infection leads to heart disease remains unknown. Here, we leveraged both mouse models and human primary cardiac cells to define the mechanisms of CHIKV heart infection. Using an immunocompeten...

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Detalles Bibliográficos
Autores principales: Noval, Maria G., Spector, Sophie N., Bartnicki, Eric, Izzo, Franco, Narula, Navneet, Yeung, Stephen T., Damani-Yokota, Payal, Dewan, M. Zahidunnabi, Mezzano, Valeria, Rodriguez-Rodriguez, Bruno A., Loomis, Cynthia, Khanna, Kamal M., Stapleford, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400619/
https://www.ncbi.nlm.nih.gov/pubmed/37537212
http://dx.doi.org/10.1038/s41467-023-40047-w

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