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Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Aminoglycosides are a class of antibiotics that bind to ribosomal RNA and exert pleiotropic effects on ribosome function. Amikacin, the semisynthetic derivative of kanamycin, is commonly used for treating severe infections with multidrug-resistant, aerobic Gram-negative bacteria. Amikacin carries th...

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Detalles Bibliográficos
Autores principales:	Seely, Savannah M., Parajuli, Narayan P., De Tarafder, Arindam, Ge, Xueliang, Sanyal, Suparna, Gagnon, Matthieu G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400623/ https://www.ncbi.nlm.nih.gov/pubmed/37537169 http://dx.doi.org/10.1038/s41467-023-40416-5

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