Colistin resistance mutations in phoQ can sensitize Klebsiella pneumoniae to IgM-mediated complement killing

Due to multi-drug resistance, physicians increasingly use the last-resort antibiotic colistin to treat infections with the Gram-negative bacterium Klebsiella pneumoniae. Unfortunately, K. pneumoniae can also develop colistin resistance. Interestingly, colistin resistance has dual effects on bacteria...

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Detalles Bibliográficos
Autores principales: van der Lans, Sjors P. A., Janet-Maitre, Manon, Masson, Frerich M., Walker, Kimberly A., Doorduijn, Dennis J., Janssen, Axel B., van Schaik, Willem, Attrée, Ina, Rooijakkers, Suzan H. M., Bardoel, Bart W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400624/
https://www.ncbi.nlm.nih.gov/pubmed/37537263
http://dx.doi.org/10.1038/s41598-023-39613-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400624/
https://www.ncbi.nlm.nih.gov/pubmed/37537263
http://dx.doi.org/10.1038/s41598-023-39613-5

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