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Mitigating biomass composition uncertainties in flux balance analysis using ensemble representations

The biomass equation is a critical component in genome-scale metabolic models (GEMs): it is used as the de facto objective function in flux balance analysis (FBA). This equation accounts for the quantities of all known biomass precursors that are required for cell growth based on the macromolecular...

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Detalles Bibliográficos
Autores principales:	Choi, Yoon-Mi, Choi, Dong-Hyuk, Lee, Yi Qing, Koduru, Lokanand, Lewis, Nathan E., Lakshmanan, Meiyappan, Lee, Dong-Yup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400880/ https://www.ncbi.nlm.nih.gov/pubmed/37547082 http://dx.doi.org/10.1016/j.csbj.2023.07.025

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