Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

OBJECTIVE: Pro-peptide precursors are processed into biologically active peptide hormones or neurotransmitters, each playing an essential role in physiology and disease. Genetic loss of function of a pro-peptide precursor results in the simultaneous ablation of all biologically-active peptides withi...

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Detalles Bibliográficos
Autores principales: Sahu, Bhavani S., Razzoli, Maria, McGonigle, Seth, Pallais, Jean Pierre, Nguyen, Megin E., Sadahiro, Masato, Jiang, Cheng, Lin, Wei-Jye, Kelley, Kevin A., Rodriguez, Pedro, Mansk, Rachel, Cero, Cheryl, Caviola, Giada, Palanza, Paola, Rao, Loredana, Beetch, Megan, Alejandro, Emilyn, Sham, Yuk Y., Frontini, Andrea, Salton, Stephen R., Bartolomucci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400922/
https://www.ncbi.nlm.nih.gov/pubmed/37482186
http://dx.doi.org/10.1016/j.molmet.2023.101781

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