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Epigenetic modulation of Drp1-mediated mitochondrial fission by inhibition of S-adenosylhomocysteine hydrolase promotes vascular senescence and atherosclerosis

AIMS: Vascular senescence, which is closely related to epigenetic regulation, is an early pathological condition in cardiovascular diseases including atherosclerosis. Inhibition of S-adenosylhomocysteine hydrolase (SAHH) and the consequent increase of S-adenosylhomocysteine (SAH), a potent inhibitor...

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Detalles Bibliográficos
Autores principales:	You, Yiran, Chen, Xu, Chen, Yu, Pang, Juan, Chen, Qian, Liu, Qiannan, Xue, Hongliang, Zeng, Yupeng, Xiao, Jinghe, Mi, Jiaxin, Tang, Yi, Ling, Wenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10400927/ https://www.ncbi.nlm.nih.gov/pubmed/37517319 http://dx.doi.org/10.1016/j.redox.2023.102828

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